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April 14 - 'Reading' Bones Can Reveal
How Fast You'll Age But Intervention Programs Can Slow The
Aging Process
Perhaps the aging process can't be stopped. But it can be
predicted, and new research from Tel Aviv University indicates
that people may live longer and lead healthier lives as a
result. Researchers have developed a new biological marker
that represents the age of a body's bones. It reveals that
the speed of physical aging is strongly influenced by genetics.
Christened the osseographic score (OSS), this new marker
can be used by doctors as a scientific tool for predicting
a person's general functioning and lifespan, says Tel Aviv
University scientist Dr. Leonid Kalichman, an instructor at
The Stanley Steyer School of Health Professions. He is a coauthor
of the study published in Biogerontology
and the American Journal of Human Biology,
which was conducted in partnership with Dr. Ida Malkin and
Prof Eugene Kobyliansky, both from the Sackler Faculty of
Medicine at Tel Aviv University.
If a doctor can determine that a person is aging "biologically
faster" than he or she should, measures such as vitamin
supplements and exercise can help slow down the process, says
Kalichman.
"While different biomarkers such as grey hair, wrinkles
or elasticity of the skin can help us estimate a person's
biological age, these features are hard to quantify,"
he says. But with the new OSS biomarker, and treatment at
a younger age, "at age 90 people can function as though
they are 30," says Kalichman.
He predicts that biological aging will be an increasingly
hot topic of study in the coming years, especially in the
western world where people are living longer than ever before.
The Tel Aviv University researchers investigated the bones
of about 400 Russian families 787 men 18 to 89 years old and
723 women 18 to 90 years old. The results of the study indicated
that men and women inherit different aging patterns. In men,
the genes expressed are more likely to influence how quickly
they will age. For women, the genes are more likely to represent
at what age visible changes in the bone will begin to appear.
The results of this new study will join a battery of other
tools used by scientists who research aging and ways to fight
it. Presently a research fellow at Boston University, Kalichman
says, "At the end of the day, the quest of scientists
and doctors is to help people function better than their chronological
age--the age written on your passport."
Source: American Friends of Tel Aviv University
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